Genetic variant linked to lupus
Researchers have identified a genetic variant which could be linked to lupus.
A team from Imperial College London published its findings in the journal Nature Genetics.
Professor Tim Vyse and his colleagues identified a new genetic variant - called OX40L - which seems to increase the risk of developing lupus. They added that the variant is carried by around one in six people in the UK and increases the risk of developing the disease by 50 per cent.
"Lupus can be a very serious condition, but because its symptoms are often similar to those of other illnesses, it can be difficult and take time to diagnose," explained Professor Vyse.
"Although it appears to have a number of environmental triggers, we are now beginning to get a clearer picture of the role that genetics also plays in the disease.
"As well as causing problems with diagnosis, lupus's many symptoms make it difficult to work out which are key to the disease."
He added that identifying specific genes involved in the process will mean that scientists can look at the disease at a molecular level. This could lead to new treatment options.
Professor Vyse also said that more patients should consider volunteering DNA samples so that more research could be easily undertaken.
"Without DNA samples from people with lupus, we would be unable to study the disease," he explained.
A spokesman for the Arthritis Research Campaign, which funds a considerable amount of research into the condition, said: "This finding could lead to more accurate tests for lupus, and hopefully better treatments in the future."
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